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Write a customer review. See all customer images. Read reviews that mention denis leary great show great series great price dennis leary love this show box set tommy gavin big fan perfect condition falling apart final season whole series stacked on top highly recommend complete series excellent series shows you will ever entire series dvds play.

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There was a problem filtering reviews right now. Please try again later. I don't know how anybody feels about Dennis Leary, I like him. He and his entire group that day were killed. They never found his body. His family buried an empty casket. I was drawn to the series because of that. I found that Mr. Leary did a damned fine job. I watched the show when it originally aired, looked forward to it every week. Watching it again, it's still Great! But can't help but wonder, how'd they get away with the profanity? Or the sex scenes? I don't remember noticing that before. I guess the times they are a-changin'.

It's a Great Show.

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I've re-watched it all except the final season - I know how it ends - and as when it originally aired - I don't want it to end. But I guess that's what makes a Great Show so Great. They never "Jump the Shark". One person found this helpful. I watched every episode of this show when it was on TV and I loved it, so I was thrilled to finally be able to buy the box set of the entire series. I have a question though about the box set. I have been ripping the disks to. I do this to all my DVDs so I can rip them once then store them away. I rip them then name the episodes just like they're listed in the guide that came with the box set.

However, when I got to "Season 6 and the Final season", which according to that guide, there's supposed to be 19 episodes, 10 in season 6 and 9 in season 7. But when I finally got through ripping them, the last five disks contained 39 episodes.

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Can someone tell me why? What are all these extra episodes? I don't even know where to start naming them as there are 20 more episodes than from what I can tell there's supposed to be. Thanks for any help. The Complete Series - Let me be very clear here - yes, the package that holds the set is sub-par You get all 26 DVD discs that would come if one purchased all of the individual season sets.

The shows on these DVD's are anamorphic widescreen - they will show as widescreen on DVD players that are capable of handling this format which should include even the cheapest models on any widescreen TV. I do own an older DVD player which does not handle the anamorphic format, and on that the show displays in letterbox format. They have english closed-captioning which is switchable through your DVD player's settings not on the discs themselves.

The discs have all of the content that you would expect on the individual season sets - featurettes, gag reels, etc. There's nothing fancy here. The only insert is a single page overlay that numbers the individual episode names for each season.

The box butterflies to expose the two spindles of DVD's. The twin spindles hold the DVD's securely, with cardboard packaging inserts to hold each stack down. As others have complained about, you might hope for better packaging - but I look at it as I'm getting everything that matters for a small percentage of the price of purchasing the individual season sets. For all that money that I've just saved, I'll purchase aftermarket cases for my DVD's and still get to enjoy everything I loved about this great series If you loved the series, you'll love this set.

I have uploaded pictures for those who want more detail on the packaging Cheers!! This show pulled no punches, and never blinked when it looked at hard things, It was often criticized by the PC crowd, but was hailed by firefighters all over the nation I personally place far more value in the opinions of the guys who run INTO burning buildings over the SJW crybabies The most disgusting language but the main actor.

Packaging is cheapest I've ever seen and NO Subtitles! The DVD quality is pretty good, however, the quality of the packaging is not that great. The glue came apart as soon as I opened it and the plastic piece holding the DVD came right off! Be careful when you purchase this! See all reviews.

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Enter giveaways for a chance to win great prizes! Amazon Sellers and Authors create new giveaways every day to promote their products. Meeting, travel to present research: No relevant financial relationships with commercial interests to disclose. Connie Etheridge and Ben Etheridge have no relevant financial relationships with commercial interests to disclose. The following individuals have no relevant financial relationships with commercial interests: Participants are advised to consult prescribing information for any products discussed.

After surgery, fractionated external beam radiation therapy is used as a standard therapy based upon early studies. Tumor treating fields have also been incorporated into the treatment guidelines for patients with supratentorial disease as a class 2A recommendation in the adjuvant setting and a class 2B recommendation for recurrent disease. There are several tumor testing options that can help to guide initial treatment for patients with glioblastoma. Imaging with MRI may provide insight into tumor burden, as well as patterns of growth and potential deficits that the patient may be facing.

Metabolic imaging modalities are also available, such as positron emission tomography scans and spectroscopy. Genetic factors may also be helpful in guiding therapy.

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The molecular O6-methylguanine-DNA-methyltransferase marker predicts a greater likelihood of deriving benefit from temozolomide therapy. This is the lone predictive marker that has been established thus far in the treatment of glioblastoma. The optimal duration of temozolomide has not yet been established. There does not appear to be additional benefit for extending temozolomide beyond 6 months. For more details, please visit http: Precision oncology is helping to hone treatment approaches for patients with glioblastoma.

Targeted therapies have been investigated to help improve survival outcomes for patients with glioblastoma, which was one of the initial tumor types analyzed by the Cancer Genome Atlas Network. Anti-VEGF agents, such as bevacizumab, have also been evaluated in the treatment of patients with glioblastoma, both in the recurrent and first-line settings.

VEGF inhibitors inhibit tumor growth and brain edema associated with vasogenic activity. Immunotherapy options for patients with glioblastoma are an active area of clinical investigation, with several studies looking at checkpoint inhibitor therapy. Other studies are looking at ways to incorporate vaccine therapy for patients with glioblastoma.

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Immunotherapy options have generally been well tolerated in clinical studies, although durable responses remain elusive. Clinicians involved in the care of patients with glioblastoma must master several factors regarding patient communication. The successful management of these patients requires a multidisciplinary effort coordinated to accurately relay prognostic information for both patients and caregivers. Most patients do not have full prognostic awareness of the incurable nature of malignant gliomas.